Aqueous Leaf Extract of <i>Moringa oleifera</i> (Moringaceae) Effectively Treats Induced Hemolytic Anemia in Wistar Rats

Introduction: Moringa oleifera was a medicinal plant generally used by populations in the food and therapeutic fields. It’s to treat anemia has been observed Djougou Zone northern Benin. To our knowledge, there were no scientific data available that have evaluated its efficacy treatment of haemolytic anemia. This what justifies this research work which phytochemical analysis, extraction evaluation anti-anemic effect carried out. Methods: Five groups five Wistar rats each formed. All rendered anemic injection phenylhydrazine hydrochloride on first two days D0 D1 except those negative control group. From second day, force-fed either with aqueous extract leaves at 200 or 300 mg/kg body weight/day, vitafer, reference drug against The positive group (anemia) not treated. Blood samples taken from all different days: D0, D2, D7, D10 D15 evaluate hemogram osmotic resistance red blood cells. Results: Phytochemical analysis revealed presence tannins, flavonoids, leucoanthocyanins, saponosides, triterpenes mucilages. A good yield obtained extraction. Both vitafer completely corrected within weeks after stimulating hemoglobin synthesis early release immature cells into bloodstream. Its seemed dose-dependent specific. Conclusion: showed can be considered exploited for transformation improved traditional medicines (ITM)